Neo-Sex Chromosome

One-sentence definition. A neo-sex chromosome is a newly derived sex chromosome formed when an autosome fuses with, or is recruited as a replacement for, an existing sex chromosome — starting a fresh cycle of sex chromosome evolution.

One-sentence analogy. A neo-sex chromosome is like a newly hired employee placed in a specialized department: once there, they quickly acquire the specialized characteristics (and limitations) of that department, often losing skills they had in the general workforce.

Why it matters. Neo-sex chromosomes reveal the speed of sex chromosome evolution. In Drosophila miranda, a neo-Y formed by a Y–autosome fusion ~1–2 million years ago has already lost or pseudogenized 40% of its ancestral autosomal genes and accumulated transposable elements — demonstrating that Y degeneration proceeds rapidly. Neo-X chromosomes in threespine sticklebacks accumulate loci for behavioral reproductive isolation even before hybrid sterility loci appear, showing that neo-sex chromosomes can drive speciation.

Where you meet it in the wiki.

Primary citation.

“In D. miranda the neo-Y, which formed by a Y to autosome fusion approximately 1–2 million years ago, has already accumulated a large number of transposable elements and 40% of the ancestral autosomal genes have been pseudogenized or lost.” — Blackmon & Demuth 2015, Finding 2

Prerequisites: heterogamety, autosome, chromosome fusion Next, learn about: recombination suppression, SA fusion

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